All plastics contain potential migrants that can affect the activity and safety of
the packaged produce.
Reprotoxicity has been demonstrated by direct contact between the migrants
and the spermatozoa. BADGE causes mainly miscarriages, while Surfynol and
lactones affect the fecundation. Surfynol affects proteins in the cells.
In most of the cases, NIAS caused reprotoxicity.
All NIAS here tested are quite common in food packaging materials;
Identification and quantification of migrants, including NIAS, is extremely
Cytometry doesn’t provide enough sensitivity and detailed information about